Removes supercoiling ahead of the replication fork.
A) DNA ligase
B) DNA primase
C) Topoisomerase
D) DNA polymerase I
E) DNA polymerase III

Question

Quizplus · Accepted Answer

Topoisomerase is responsible for removing supercoiling ahead of the replication fork by cutting the DNA strands, unwinding them and then resealing the cut ends. DNA ligase is responsible for sealing the gaps between the Okazaki fragments during lagging strand synthesis. DNA primase is responsible for synthesizing a short RNA primer that is complementary to the DNA template strand. DNA polymerase I is responsible for replacing the RNA primers with DNA nucleotides and DNA polymerase III is responsible for elongating the leading and lagging strands during DNA synthesis.

Removes Supercoiling Ahead of the Replication Fork