In E. coli, a mutation in the genes encoding which of the following proteins would disable the ability of the cell to recognize double-stranded breaks and conduct recombination during meiosis?
A) RecG
B) RecA
C) RecBCD
D) RuvABC

Question

Quizplus · Accepted Answer

The RecBCD complex is responsible for DNA end processing and loading RecA onto single-stranded DNA to form a nucleoprotein filament during homologous recombination. Without this complex, the cell is unable to recognize and respond to double-stranded DNA breaks during meiosis. The other proteins listed, RecG and RuvABC, are involved in later stages of homologous recombination, while RecA is necessary for strand exchange during recombination.

In E Coli, a Mutation in the Genes Encoding Which of of the Following