For a DNA strand that contains the sequence AGT in the 5' to 3' direction, what nucleotides are found on the other DNA strand in the 5' to 3' direction?
A) ACT
B) TGA
C) AGT
D) TCA
E) GTA By Chargaff's rules, T hydrogen bonds with A, C with G, and A with T. Since the opposite strand runs antiparallel, the correct order of these nucleotides is ACT.

Question

Quizplus · Accepted Answer

According to Chargaff's rules, T always bonds with A, and C always bonds with G. Therefore, the complementary strand to AGT must contain TCA in the 5' to 3' direction, which is equivalent to the ACT sequence in the 3' to 5' direction (since DNA strands run antiparallel). Therefore, choice (A) is the best choice.

For a DNA Strand That Contains the Sequence AGT in the 5