Which of the following processes generates a proton-motive force in mitochondria?
A) The flow of protons through ATP synthase down their concentration gradient.
B) The reduction of NAD⁺ by the first electron carrier in the electron transport chain.
C) Lowering of pH in the mitochondrial matrix.
D) Pumping of hydrogen ions from the mitochondrial matrix across the inner membrane and into the intermembrane space.

Question

Quizplus · Accepted Answer

The pumping of hydrogen ions from the mitochondrial matrix across the inner membrane and into the intermembrane space generates a proton-motive force by creating a concentration gradient of protons. This gradient can be used by ATP synthase to produce ATP from ADP and Pi. The other options (A, B, and C) are part of the process of oxidative phosphorylation, but do not directly generate a proton-motive force.

Which of the Following Processes Generates a Proton-Motive Force in Mitochondria