At Puberty, an Adolescent Female Body Changes in Both Structure

At puberty, an adolescent female body changes in both structure and function of several organ systems, primarily under the influence of changing concentrations of oestrogen and other steroid hormones. How can one hormone, such as oestrogen, mediate so many effects?

A) Oestrogen is produced in very large concentration by nearly every tissue of the body.
B) Each cell responds in the same way when steroids bind to the cell surface.
C) Oestrogen is kept away from the surface of any cells, not able to bind it at the surface.
D) Oestrogen binds to specific receptors inside many kinds of cells, each with different responses.