In which order do the necessary enzymes act to repair a thymine dimer by nucleotide excision repair?
A) nuclease, DNA polymerase, RNA primase
B) helicase, DNA polymerase, DNA ligase
C) DNA ligase, nuclease, helicase
D) DNA polymerase, RNA polymerase, DNA ligase
E) nuclease, DNA polymerase, DNA ligase

Question

Quizplus · Accepted Answer

Nucleotide excision repair involves the removal of a section of DNA containing the damaged region, followed by resynthesis of the missing nucleotides. This process involves several enzymes including a nuclease to cut the damaged DNA, DNA polymerase to fill in the missing nucleotides, and DNA ligase to seal the remaining gaps. Therefore, the correct order of enzyme action is nuclease, DNA polymerase, and DNA ligase, which corresponds to choice E.

In Which Order Do the Necessary Enzymes Act to Repair