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Curare is a potent neurotoxin extracted from the Strychnos toxifera plant in Central and South America. Indigenous peoples of South America apply curare to arrows, which they used to hunt and kill animals. Curare acts at synapses between motor neurons and skeletal muscle cells. When a motor neuron synapses with a skeletal muscle cell, the skeletal muscle cell may be stimulated or inhibited just like postsynaptic neurons are. Curare acts by binding temporarily to acetylcholine receptors on the postsynaptic cell and prevents acetylcholine from binding.
-What effect does curare likely have on the postsynaptic cell?
A) prevents voltage-gated sodium channels from opening
B) hyperpolarizes the postsynaptic cell
C) stimulates muscle contraction
D) depolarizes the presynaptic cell

Question

Quizplus · Accepted Answer

Curare prevents acetylcholine from binding to its receptors, which inhibits the opening of ligand-gated sodium channels, thereby preventing depolarization and subsequent muscle contraction.

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