When subcellular components from disrupted cells are separated using centrifugation, the primary factor that determines whether a specific cellular component remains in the liquid solution or ends up in the pellet is
A) the relative size and weight of the component.
B) the relative solubility of the component.
C) how hydrophobic the component is.
D) the carbohydrate composition of the component.

Question

Quizplus · Accepted Answer

Centrifugation separates subcellular components based on their size and weight. Therefore, the primary factor that determines whether a specific component will stay in the liquid or end up in the pellet is its relative size and weight. Generally, larger and heavier components will pellet at a lower speed than smaller and lighter components.

When Subcellular Components from Disrupted Cells Are Separated Using Centrifugation