Which of the Following Is a Major Cause of the Size

Which of the following is a major cause of the size limits for certain types of cells?

A) limitation on the strength and integrity of the plasma membrane as cell size increases
B) the difference in plasma membranes between prokaryotes and eukaryotes
C) evolutionary progression in cell size; more primitive cells have smaller sizes
D) the need for sufficient surface area to support the cell's metabolic needs
E) rigid cell walls that limit cell size expansion