Mutations that result in single amino acid substitutions in an enzyme
A) cannot affect the activity or properties of the enzyme.
B) will almost always destroy the activity of the enzyme.
C) will often change the substrate specificity of the enzyme.
D) may change the enzyme's optimal temperature or optimal pH.
E) may, in rare cases, cause the enzyme to run reactions in reverse.

Question

Quizplus · Accepted Answer

Mutations that result in single amino acid substitutions in an enzyme may change the enzyme's optimal temperature or optimal pH. This can lead to altered activity or stability under certain conditions. However, it is not always the case that a single amino acid substitution will have a significant effect on the enzyme's activity or properties. Answer A is incorrect as mutations can certainly affect enzyme activity and properties. Answer B is incorrect as it is unlikely that all single amino acid substitutions would completely destroy enzyme activity. Answer C is possible, but not always the case with single amino acid substitutions. Answer E is not a likely outcome of a single amino acid substitution.

Mutations That Result in Single Amino Acid Substitutions in an Enzyme