There is a mutation in a promoter next to a gene such that RNA polymerase can never bind. What steps must occur for the gene to be transcribed?
A) An activator protein must bind an enhancer.
B) The DNA must physically bend so that the activator is close to the promoter.
C) Transcription factors must bind to the activator and promoter.
D) Transcription will never take place in this specific example.

Question

Quizplus · Accepted Answer

Given that RNA polymerase can never bind to the promoter due to a mutation, transcription cannot occur, rendering all other steps to facilitate transcription irrelevant in this context.

There Is a Mutation in a Promoter Next to a Gene