Source: Adapted from C. A. Huether et al., Maternal age specific risk rate estimates for Down syndrome among live births in whites and other races from Ohio and Metropolitan Atlanta, 1970-1989, Journal of Medical Genetics 35: 482-90 (1998). Figure 8.20B Maternal age and incidence of Down syndrome
-Many cancer drugs known as "antimitotics" target microtubules. What is the first stage of mitosis at which these drugs are likely to have an effect?
A) anaphase
B) metaphase
C) prophase
D) telophase

Question

Source: Adapted from C. A. Huether et al., Maternal age specific risk rate estimates for Down syndrome among live births in whites and other races from Ohio and Metropolitan Atlanta, 1970-1989, Journal of Medical Genetics 35: 482-90 (1998). Figure 8.20B Maternal age and incidence of Down syndrome
-Many cancer drugs known as "antimitotics" target microtubules. What is the first stage of mitosis at which these drugs are likely to have an effect?
A) anaphase 
B) metaphase 
C) prophase 
D) telophase

Quizplus · Accepted Answer

Antimitotics disrupt microtubule functions, which are crucial for chromosome condensation and spindle formation starting in prophase, the first stage of mitosis affected.