Approximately one in every three : T cells expresses two different rearranged TCR chain proteins. Yet T cells are still considered to have 'clonal specificity' for recognizing antigen. The reason for asserting that each T cell has a single functional specificity for recognizing antigen is that:
A) Only one of the two TCR chains expressed by a T cell will pair with its TCR chain.
B) T cells expressing two different TCR chains will die by apoptosis when they are activated.
C) Only one T-cell receptor expressed by each T cell will recognize peptide presented by self-MHC molecules.
D) The majority of T cells in an individual will never encounter their specific peptide-MHC ligand and so will not be part of an immune response.
E) The majority of T cells are self-reactive and therefore eliminated during their development in the thymus.
Correct Answer:
Verified
Q27: If one swapped the regulatory elements
Q28: The final stages of T cell
Q29: An infant is admitted to the
Q30: MHC class II molecules expressed on
Q31: Current evidence indicates that >95% of
Q32: Like the
Q33: Two mutant lines of mice have been
Q35: Experiments performed with T-cell receptor transgenic mice
Q36: While many cell types in the thymus
Q37: T cell development in the thymus shares
Unlock this Answer For Free Now!
View this answer and more for free by performing one of the following actions
Scan the QR code to install the App and get 2 free unlocks
Unlock quizzes for free by uploading documents