HIV encodes several proteins that function to promote viral replication, packaging, and budding from host CD4 T cells. In addition to inhibiting cell-intrinsic antiviral mechanisms and down-regulating surface expression of MHC class I and class II molecules, these proteins function to:
A) Induce constitutive activation of NF- B
B) Promote nuclear localization of NFAT
C) Block nuclear export of unspliced viral RNA
D) Up-regulate surface expression of CD4
E) Induce robust, sustained CD4 T cell activation
Correct Answer:
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