TB 8.066 The ER reportedly contains sensors that monitor the concentration of unfolded or misfolded proteins in the lumen.One proposal suggests that the sensors are normally kept in an inactive state by ______,particularly ______.
A)molecular chaperones,ribosomes
B)proteasomes,BiP
C)molecular chaperones,BiP
D)enzymes,ER
E)molecular chaperones,Rubisco

Question

Quizplus · Accepted Answer

The sentence indicates that the sensors are kept inactive by something, and the options include molecular chaperones, proteasomes, enzymes or Rubisco. However, option C is the only one that provides a plausible answer because BiP is a molecular chaperone that is known to interact with unfolded or misfolded proteins in the endoplasmic reticulum lumen. Therefore, option C is the best choice.

TB 8066 the ER Reportedly Contains Sensors That Monitor the Concentration