What circumstantial evidence supports the proposed role of the Rabs in recruiting cytosolic tethering proteins to specific membrane surfaces?
A)With over 60 Rab genes identified in humans,Rabs constitute the most diverse group of proteins involved in membrane trafficking.
B)Rabs have the potential of giving each cell compartment a unique surface identity.
C)Different Rabs have been found to be associated with different membrane compartments.
D)The preferential localization of Rabs allows them to recruit the proteins involved in targeting specificity.
E)All of these are correct statements that support the proposed role of the Rabs.

Question

Quizplus · Accepted Answer

All of the statements given provide circumstantial evidence to support the proposed role of Rabs in recruiting cytosolic tethering proteins to specific membrane surfaces. The large number and diversity of Rab genes indicate their wide range of functional roles, including their potential to give each cell compartment a unique surface identity. Different Rabs have been found to be associated with different membrane compartments, indicating their specificity in membrane trafficking. The preferential localization of Rabs allows them to recruit the proteins involved in targeting specificity, supporting their role in recruiting cytosolic tethering proteins.

What Circumstantial Evidence Supports the Proposed Role of the Rabs