The helix-turn-helix is a common protein motif that is able to interact with DNA in the major grooves by both electrostatic and specific interactions between amino acids of the helix and the bases of the DNA.

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The helix-turn-helix motif is a well-known type of DNA-binding motif that is able to interact with DNA in the major grooves through both electrostatic and specific interactions between amino acids of the helix and the DNA bases. This motif is commonly found in transcription factors and other DNA-binding proteins.

The Helix-Turn-Helix Is a Common Protein Motif That Is Able