Arrange the steps involved in folding of globular proteins into a proper sequencE.
A."Molten globule" formation of assembled domains.
B.Formation of domains through cooperative aggregation of folding nuclei.
C.Adjustment in the conformation of domains.
D.Rapid and reversible formation of local secondary structurE.E.Final protein monomer formation.
A) A, B, C, D, E.
B) B, C, E, A, D
C) D, C, B, A, E
D) D, B, A, C, E
E) B, D, C, A, E

Question

Quizplus · Accepted Answer

The correct sequence for the folding of globular proteins starts with the rapid and reversible formation of local secondary structure (D), followed by the formation of domains through cooperative aggregation of folding nuclei (B). Next, a "molten globule" state is formed as these domains assemble (A), which then undergoes adjustment in the conformation of domains (C), leading to the final protein monomer formation (E).

Arrange the Steps Involved in Folding of Globular Proteins into a Proper