All are characteristics of the enzyme hexokinase EXCEPT:
A) It is not highly specific and will catalyze phosphorylation of a number of hexoses at the six position.
B) Hexoses bind the active site and induce a solvent inaccessible fit to the hexose.
C) Glycerol may fit into the active site, but it does not bind to induce a conformational change necessary for catalysis.
D) When a hexose binds the active site, the active site is modified to promote changes in the substrate to a transitional-state intermediate.
E) All are true.

Question

Quizplus · Accepted Answer

All the statements provided are true characteristics of hexokinase. Hexokinase is not highly specific and can phosphorylate several hexoses, hexoses binding induce a conformational change, glycerol can fit but doesn't induce the necessary change for catalysis, and the binding of a hexose modifies the active site to promote transition to an intermediate state.

All Are Characteristics of the Enzyme Hexokinase EXCEPT