CO2 fixation is one of the most critical reactions on earth. Which of the following are elements of the reaction catalyzed by the RUBISCO enzyme?
A) Mg2+ acts as a Lewis acid, binding to CO2 and making it more susceptible to nucleophilic attack
B) The 6-carbon enzyme-bound intermediate that forms is split into 2 molecules of 3-phosphoglycerate
C) Biotin is attached to a Lys residue in the active site and serves a critical role in the activation of CO2
D) ATP is required for the activation of CO2 prior to its reaction with ribulose-1,5-bisphosphate
E) Both a and b occur
Correct Answer:
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