All are correct statements regarding the protein degradation process involving ubiquitin EXCEPT: A) The modified protein is degraded by an ATP-dependent protease complex. B) The ubiquitin binding to the protein to be degraded leads to a novel branched protein. C) The ubiquitin is covalently attached to a cysteine residue in the protein to be degraded. D) Three additional proteins (E₁, E₂, and E₃) are involved in the ligation of ubiquitin to the protein. E) Ubiquitin is a highly conserved protein.

Question

Quizplus · Accepted Answer

Ubiquitin is covalently attached to a lysine residue on the target protein, not a cysteine residue. This is a key step in tagging proteins for degradation.

All Are Correct Statements Regarding the Protein Degradation Process Involving