Which of the following is correctly defined with regards to catecholamines?
A) reserpine increases brain monoamine levels by upregulation of vesicle production
B) bromocriptine is a dopamine antagonist linked to some Parkinson's disease indidences
C) cocaine binds to monoamine reuptake transporters on the presynaptic membrane thus prolonging the effects of monoamines
D) Prozac is a highly specific dopamine reuptake inhibitor
E) none of the above

Question

Quizplus · Accepted Answer

Cocaine binds to monoamine reuptake transporters on the presynaptic membrane, thus preventing the reuptake of monoamines and prolonging their effects. This leads to an increase in the concentration of catecholamines such as dopamine, norepinephrine, and epinephrine in the synaptic cleft. Reserpine, on the other hand, depletes monoamine levels by blocking the vesicular monoamine transporter, while bromocriptine is a dopamine agonist used to treat Parkinson's disease by stimulating dopamine receptors. Prozac is a selective serotonin reuptake inhibitor and has no significant effect on dopamine levels. Therefore, the correct option is C.

Which of the Following Is Correctly Defined with Regards to Catecholamines