Which choice could provide the product. _______ + _______
A)benzyl chloride,propyne
B)benzyl iodide,acetylene
C)phenyl bromide,1-butyne
D)phenyl bromide,2-butyne
E)phenyl iodide,ethene

Question

Which choice could provide the product. _______ + _______  
A)benzyl chloride,propyne 
B)benzyl iodide,acetylene 
C)phenyl bromide,1-butyne 
D)phenyl bromide,2-butyne 
E)phenyl iodide,ethene

Quizplus · Accepted Answer

The reaction suggested in the question is the Sonogashira coupling reaction, in which an aryl or vinyl halide reacts with a terminal alkyne, typically in the presence of a palladium catalyst and a base, to form a new carbon-carbon bond. Among the given choices, only phenyl bromide and 1-butyne can react in this way to form the desired product. The other options either lack a terminal alkyne or have a halide that is unlikely to undergo the reaction under the given conditions. Therefore, choice C is the best option.

Which Choice Could Provide the Product