Coupling benzyl bromide with propene,using a Pd catalyst,is an example of ____.
A)Stille Coupling and Carbonylation
B)Suzuki-Miyaura Coupling
C)Heck-Mizoroki Coupling
D)Sonogashira Coupling
E)Gilman Reagent-Mediated Coupling

Question

Quizplus · Accepted Answer

The given reaction involves the coupling of an aryl halide (benzyl bromide) with an alkene (propene) using a palladium catalyst. This is a classic example of the Heck-Mizoroki coupling reaction. The reaction proceeds via the oxidative addition of aryl halide to the Pd(0) catalyst, followed by the formation of a Pd-alkene intermediate and subsequent reductive elimination of the desired coupled product.

Option A (Stille coupling and carbonylation) involves coupling of an organotin compound with an aryl halide, followed by carbonylation. Option B (Suzuki-Miyaura coupling) involves coupling of an aryl or vinyl boronic acid with an aryl halide or vinyl halide. Option D (Sonogashira coupling) involves coupling of an aryl or vinyl halide with a terminal alkyl or alkynyl compound. Option E (Gilman reagent-mediated coupling) involves coupling of an organomagnesium or organolithium reagent with an alkyl or aryl halide.

Coupling Benzyl Bromide with Propene,using a Pd Catalyst,is an Example