Which is the best method for the synthesis of tert-butyl methyl ether? A)CH₃ONa + (CH₃)₃CBr $\to$ B)(CH₃)₃CONa + CH₃I $\to$ D)(CH₃)₃CONa + CH₃OCH₃ $\to$ E)CH₃ONa + (CH₃)₃COH $\to$

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The best method for the synthesis of tert-butyl methyl ether is the Williamson ether synthesis. In this method, an alkoxide ion is used as the nucleophile to attack the carbon atom of an alkyl halide, resulting in the formation of an ether. In this case, the alkoxide ion is generated using NaOH and the alcohol in the presence of CH3I, giving rise to the alkylating agent. Therefore, option B, which uses CH3I as the alkylating agent and NaOCH3 as the nucleophile, is the best choice.

Which Is the Best Method for the Synthesis of Tert-Butyl →\to→

Which Is the Best Method for the Synthesis of Tert-Butyl $\to$