Regarding the use of potassium tert-butoxide as a base in E2 reactions,it is incorrect to state that: A)this base is more effective than ethoxide ion,because it (KOt-Bu)is the more basic of the two. B)it tends to give the anti-Zaitsev,i.e.,Hofmann,product. C)it is more reactive in dimethyl sulfoxide than it is in tert-butyl alcohol. D)it favors E2 reactions over competing S_N2 reactions. E)it will form,predominantly,the more stable alkene.

Question

Quizplus · Accepted Answer

Potassium tert-butoxide is a bulky base, which tends to favor the formation of the less substituted, less stable alkene (Hofmann product) rather than the more stable alkene (Zaitsev product).

Regarding the Use of Potassium Tert-Butoxide as a Base in E2