Which of the following statements about necrosis is true?
A) It requires ATP.
B) It does not cause inflammation.
C) It may occur when cells are damaged by toxins.
D) It produces nucleosome-sized pieces of chromatin.
E) It results in fragmentation of the cell.

Question

Quizplus · Accepted Answer

Necrosis is a type of cell death that occurs due to the cellular injury caused by factors such as toxins, infections, trauma or lack of blood flow. These insults overwhelm the cells' ability to maintain homeostasis and repair themselves, leading to their demise. Necrosis does not require ATP, and it triggers inflammation as the cell's contents are released into the surrounding tissue, activating immune cells. This response forms the basis of an inflammatory reaction, which is particularly evident in acute injuries, such as a heart attack or stroke. Necrosis often results in swelling of the cell and eventual fragmentation, but the chromatin is not divided into nucleosome-sized pieces as is the case with apoptosis.

Which of the Following Statements About Necrosis Is True