Which of the following is the correct order of events by which a protein is delivered to its cellular destination?
A) A signal sequence binds to a docking protein, a membrane channel is formed, chaperonins unfold the protein, the protein enters the organelle, and the protein refolds.
B) A membrane channel is formed, a signal sequence binds to a docking protein, chaperonins unfold the protein, the protein enters the organelle, and the protein refolds.
C) Chaperonins unfold the protein, a signal sequence binds to a docking protein, a membrane channel is formed, the protein enters the organelle, and the protein refolds.
D) A membrane channel is formed, chaperonins unfold the protein, a signal sequence binds to a docking protein, the protein enters the organelle, and the protein refolds.
E) A signal sequence binds to a docking protein, a transmembrane-gated channel opens, and the protein enters the organelle.
Correct Answer:
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