In DNA, 5-methylcytosine
A) forms a base pair with adenine.
B) is not recognized by DNA polymerase.
C) is related to transcriptional silencing of genes.
D) does not occur at promoters.
E) is an irreversible modification of cytosine.

Question

Quizplus · Accepted Answer

5-methylcytosine is related to transcriptional silencing of genes. Methylation of cytosine at position 5 on the pyrimidine ring is an important type of DNA modification that can result in regulation of gene expression. Methylation of cytosine is a widespread modification of DNA in eukaryotes, and 5-methylcytosine is particularly enriched in regions of the genome that are transcriptionally silent.

In DNA, 5-Methylcytosine