If a G protein were unable to release its bound nucleotide but could hydrolyze it, signal transduction would
A) cease.
B) be continuous.
C) be unaffected.
D) be constantly switching on and off.
E) be unpredictable.

Question

If a G protein were unable to release its bound nucleo­tide but could hydrolyze it, signal transduction would
A) cease.
B) be continuous.
C) be unaffected.
D) be constantly switching on and off.
E) be unpredictable.

Quizplus · Accepted Answer

If a G protein cannot release its bound nucleotide, it cannot exchange GDP for GTP, which is necessary for activation. Therefore, signal transduction would cease.

If a G Protein Were Unable to Release Its Bound