Which is a protein that can be translocated from cytosol to nucleus during cytokine-initiated signaling?
A) Interferon
B) JAK
C) NFkB
D) SMAD
E) Src

Question

Quizplus · Accepted Answer

NFkB is a transcription factor that is activated through cytokine-initiated signaling pathways. In its inactive form, it is sequestered in the cytosol by a protein called IkB. Cytokine signaling leads to the activation of an enzyme called IKK, which phosphorylates IkB causing its degradation. This releases NFkB, allowing it to translocate to the nucleus and activate gene transcription.

Which Is a Protein That Can Be Translocated from Cytosol