What happens when SMADs dimerize?
A) A protein kinase activity is revealed and SMAD autophosphorylates
B) Nuclear location sequences are exposed
C) SH3 domains bind
D) The βγ subunits dissociate from the α subunit
E) The folding of SMAD becomes more compact

Question

Quizplus · Accepted Answer

Dimerization exposes nuclear localization sequences, which allows the SMAD complex to be transported into the nucleus to regulate gene expression.

What Happens When SMADs Dimerize