After a ligand-receptor complex enters a cell, how is the ligand disaggregated from the receptor so that the receptor can be reincorporated in the cell membrane?
A) Alteration of lysosomal pH separates the molecules
B) Both return to membrane, and ligand is degraded extracellularly
C) Covalent binding of two ligands to each other
D) Degradation of receptor and ligand in the lysosome
E) Transfer to nucleus where ligand binds DNA

Question

Quizplus · Accepted Answer

Alteration of lysosomal pH is a key mechanism by which ligands are disaggregated from their receptors after the ligand-receptor complex enters a cell. This change in pH within the lysosome facilitates the dissociation of the ligand from the receptor, allowing the receptor to be recycled back to the cell membrane.

After a Ligand-Receptor Complex Enters a Cell, How Is the Ligand