Why are K_Dand EC₅₀usually not the same? A) Not all receptors are capable of activating cell response B) Not all receptors are capable of binding ligand C) Some receptors are inactive D) Some receptors bind more than one ligand E) The cell has "spare receptors"

Question

Quizplus · Accepted Answer

The presence of "spare receptors" means that not all receptors need to be occupied to elicit a full response, leading to a difference between K_D (dissociation constant) and EC₅₀ (concentration for half-maximal response).

Why Are KD and EC50 usually Not the Same

Why Are K_Dand EC₅₀usually Not the Same