Which of the following is LEAST likely to affect the Vmax of an enzyme?
A) A change in pH
B) A change in temperature
C) Addition of a noncompetitive inhibitor
D) Addition of a competitive inhibitor
E) Addition of an irreversible inhibitor

Question

Quizplus · Accepted Answer

Vmax, the maximum rate of an enzyme-catalyzed reaction when the enzyme is saturated with substrate, is not affected by competitive inhibitors. Competitive inhibitors increase the Km (the substrate concentration at which the reaction rate is half of Vmax) because they compete with the substrate for binding to the active site, but they do not affect the Vmax since the inhibition can be overcome by increasing substrate concentration.

Which of the Following Is LEAST Likely to Affect the Vmax