Each of the following statements about the Michaelis-Menten equation is correct EXCEPT which one?
A) The equation describes a hyperbolic curve.
B) The Michaelis constant of an enzyme-substrate pair would be expected to change with a change in pH of the assay mixture.
C) For a group-specific enzyme, the substrate with the largest Km is the one which binds most strongly to the active site.
D) The Michaelis constant is expressed in units of molarity.
E) The Km is equal to the substrate concentration yielding a velocity one-half of the Vmax.

Question

Quizplus · Accepted Answer

For a group-specific enzyme, the substrate with the largest Km is actually the one with the weakest binding to the active site. This is because a larger Km value indicates a lower affinity of the enzyme for that particular substrate.

Each of the Following Statements About the Michaelis-Menten Equation Is