In the case of noncompetitive inhibition
A) the inhibitor generally resembles the substrate.
B) the inhibition can be overcome by raising the substrate concentration.
C) Ki is the concentration of inhibitor required for half maximal inhibition.
D) a high Ki means that the inhibitor has a high affinity for the enzyme.
E) the inhibitor is commonly the product of the enzymatic reaction.

Question

Quizplus · Accepted Answer

Noncompetitive inhibition is characterized by a situation where the inhibitor does not compete with the substrate for the enzyme's active site. Instead, it binds to a different site on the enzyme, altering its activity. The Ki value represents the concentration of inhibitor needed to achieve half-maximal inhibition, which is a measure of the inhibitor's potency.

In the Case of Noncompetitive Inhibition