All of the following are characteristic of the tense form of hemoglobin EXCEPT
A) Some N-terminal amino and histidine groups have lowered pKs.
B) the subunit structure is stabilized by ionic bonds.
C) the molecule can bind bis-phosphoglycerate (BPG).
D) the molecule has a reduced affinity for oxygen.
E) the molecule has an increased affinity for carbon dioxide.

Question

Quizplus · Accepted Answer

The tense (T) form of hemoglobin is characterized by a lower affinity for oxygen, stabilization by ionic bonds, and the ability to bind bis-phosphoglycerate (BPG), which further reduces its affinity for oxygen. It also has an increased affinity for carbon dioxide. However, the statement about N-terminal amino and histidine groups having lowered pKs does not describe a characteristic of the tense form of hemoglobin; instead, it is more related to the changes in the protein structure that affect its function but not specifically characteristic of the T state regarding oxygen affinity or binding.

All of the Following Are Characteristic of the Tense Form