The P50 value of hemoglobin is higher than normal in all of the following conditions EXCEPT A) low pH. B) high PCO₂. C) low 2,3-bisphosphoglycerate. D) mutant hemoglobin with low oxygen affinity.

Question

Quizplus · Accepted Answer

The P50 value of hemoglobin is a measure of the oxygen affinity of hemoglobin; a higher P50 value indicates a lower affinity for oxygen. Conditions that lower hemoglobin's affinity for oxygen, such as low pH (A), high 2,3-bisphosphoglycerate (B), and mutant hemoglobin with low oxygen affinity (D), would increase the P50 value. However, low 2,3-bisphosphoglycerate (C) would increase hemoglobin's affinity for oxygen, thus lowering the P50 value, making it the exception.

The P50 Value of Hemoglobin Is Higher Than Normal in All