Initiation of eukaryotic translation is directly inhibited by which of the following?
A) acetylation of histone H1
B) phosphorylation of AP1 (activator protein-1)
C) phosphorylation of eIF2 (eukaryotic initiation factor 2)
D) acetylation of SRP (signal recognition particle)

Question

Quizplus · Accepted Answer

Phosphorylation of eIF2 directly inhibits eukaryotic translation initiation. This occurs in response to stress signals and leads to a decrease in global translation initiation. Acetylation of histone H1 and SRP do not directly affect translation initiation, and phosphorylation of AP1 is involved in transcriptional regulation, not translation.

Initiation of Eukaryotic Translation Is Directly Inhibited by Which of the Following