In eukaryotes, RNA polymerase II
A) is the most alpha-amanitin resistant polymerase.
B) is responsible for formation of tRNAs and other small RNAs.
C) often initiates transcription at complex promoters containing enhancers, silencers and TATA sequences.
D) terminates RNA synthesis and releases the RNA chain at AATAA sequences specifying end formation and polyadenylation.
E) normally utilizes bidirectional promoters.

Question

Quizplus · Accepted Answer

RNA polymerase II typically initiates transcription at complex promoters that contain enhancers, silencers, and a TATA box sequence. These sequences help to regulate the transcriptional activity of the gene.

Answer: A 
 RNA polymerase II is the least sensitive to alpha-amanitin, a toxin that specifically inhibits RNA polymerase II activity.

Answers B, D, and E are incorrect. RNA polymerase III is responsible for small RNA synthesis (like tRNAs), RNA polymerase II does not terminate RNA synthesis at specific end sequences (AATAA), and bidirectional promoters are typically utilized by RNA polymerase II and III.

In Eukaryotes, RNA Polymerase II