Information indicating that the final conformation of a protein is determined by the amino acid sequence in its polypeptide chains was obtained from
A) difference spectroscopy.
B) reversible denaturation.
C) atomic adsorption.
D) hydrodynamic analysis.
E) sequence analysis.

Question

Quizplus · Accepted Answer

Reversible denaturation experiments, notably those conducted by Christian Anfinsen, demonstrated that a protein can refold into its native structure after denaturation, indicating that all the information required for folding is contained within the primary amino acid sequence.

Information Indicating That the Final Conformation of a Protein Is