All of the following statements concerning DNA are correct EXCEPT
A) Base-stacking involves the interaction of aromatic pi-electron orbitals and contributes to the stability of the double helix.
B) Denatured DNA shows an increased extinction coefficient at 260 nm as compared to double-stranded DNA.
C) DNA that is rich in G and C shows a higher melting temperature.
D) The nucleotides are joined through glycosidic bonds.
E) The two strands have opposite polarity (5'-and 5').

Question

All of the following statements concerning DNA are correct EXCEPT
A) Base-stacking involves the interaction of aromatic pi-electron orbitals and contributes to the stability of the double helix.
B) Denatured DNA shows an increased extinction coefficient at 260 nm as compared to double-stranded DNA.
C) DNA that is rich in G and C shows a higher melting temperature.
D) The nucleotides are joined through glycosidic bonds.
E) The two strands have opposite polarity (5'->and >5').

Quizplus · Accepted Answer

Nucleotides in DNA are joined through phosphodiester bonds, not glycosidic bonds. Glycosidic bonds are involved in attaching the sugar component of the nucleotide to the nitrogenous base, not in linking nucleotides together in the DNA strand.

All of the Following Statements Concerning DNA Are Correct EXCEPT