The drugs that produce the most extreme alterations of consciousness are narcotics such as heroin.

Name: The drugs that produce the most extreme alterations of consciousness are narcotics such as heroin.
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Narcotics like heroin primarily act as pain relievers and can induce a state of euphoria, but psychedelics such as LSD, psilocybin (magic mushrooms), and DMT are known to produce the most extreme alterations of consciousness, including profound changes in perception, mood, and thought.

The Drugs That Produce the Most Extreme Alterations of Consciousness