Signals from the extracellular matrix to the cytoskeleton may be transmitted by ________.
A) fibronectin
B) proteoglycans
C) integrins
D) collagen
E) middle lamella

Question

Quizplus · Accepted Answer

Integrins are transmembrane proteins that link the extracellular matrix to the cytoskeleton. They bind to components of the extracellular matrix, such as fibronectin or collagen, on one end and to cytoskeletal proteins, such as actin, on the other end, allowing for communication between the outside environment and the cell's internal machinery. Proteoglycans and the middle lamella are important components of the extracellular matrix, but they do not directly transmit signals to the cytoskeleton.

Signals from the Extracellular Matrix to the Cytoskeleton May Be