If the DNA sequence was substantially altered from one of the following, which would prevent the binding of the TATA-binding protein (TBP)?
A) RNA polymerase
B) the point where transcription begins
C) the promoter
D) promoter-proximal elements
E) histone acetyl transferases (HATS)

Question

Quizplus · Accepted Answer

The TATA-binding protein (TBP) binds to the TATA box sequence, which is located in the promoter region of a gene. If this DNA sequence is substantially altered, it will prevent the binding of TBP and therefore hinder the initiation of transcription. Thus, the correct answer is the promoter (choice C). None of the other choices directly involve TBP binding or the TATA box sequence.

If the DNA Sequence Was Substantially Altered from One of the Following