Which of the following is true of leptin?
A) Leptin is a product of protein metabolism.
B) Leptin levels are decreased during overeating and obesity.
C) Mutations of the leptin gene are the most common cause of obesity.
D) Plasma leptin levels are related to body fat content only in obese persons.
E) Obese humans have high plasma leptin levels and are insensitive to leptin injection.

Question

Quizplus · Accepted Answer

Leptin is primarily produced by adipose tissue and regulates body weight by decreasing appetite and increasing energy expenditure. Obese individuals often have high levels of leptin, but are resistant to its effects, leading to continued overeating and weight gain. Mutations of the leptin gene are rare and not the most common cause of obesity.

Which of the Following Is True of Leptin