Which of the following is an explanation of hippocampal damage produced by anoxia?
A) Anoxia reduces the release of glutamate.
B) Glycine terminals are found in the hippocampus.
C) Field CA3 of the hippocampus is rich in NMDA receptors.
D) Activation of NMDA receptors produces an accumulation of calcium ions, which is toxic to the neuron.
E) Anoxia releases glycine, a toxic neurotransmitter.

Question

Quizplus · Accepted Answer

Activation of NMDA receptors produces an accumulation of calcium ions, which is toxic to the neuron. Anoxia leads to a decrease in oxygen supply to neurons, which prevents the removal of excess calcium ions from neurons. This results in an accumulation of calcium ions in the synaptic cleft, leading to hippocampal damage.

Which of the Following Is an Explanation of Hippocampal Damage