Neurotransmitter release from the presynaptic membrane is triggered by the
A) activation of the sodium-potassium pumps.
B) arrival of an EPSP at the axon terminal.
C) influx of calcium ions into the axon terminal.
D) hyperpolarization of the axon membrane.
E) opening of channels within the microtubules.

Question

Quizplus · Accepted Answer

Neurotransmitter release is triggered by the influx of calcium ions into the axon terminal. This occurs when an action potential depolarizes the membrane of the axon terminal, causing voltage-gated calcium channels to open and allowing calcium to enter the cell. The increase in intracellular calcium concentration triggers the release of neurotransmitter vesicles into the synaptic cleft.

Neurotransmitter Release from the Presynaptic Membrane Is Triggered by the