The induction of long-term potentiation in the hippocampus would be blocked by
A) a drug such as AP5 that blocks NMDA receptors.
B) using high-frequency electrical pulses.
C) a drug that activates NMDA receptors.
D) injection into the postsynaptic cell of a drug that activates calcium ions.
E) infusion of glutamate into the hippocampus.

Question

Quizplus · Accepted Answer

The induction of long-term potentiation (LTP) in the hippocampus is heavily reliant on the activation of NMDA receptors. Therefore, blocking these receptors with a drug like AP5 would prevent LTP from occurring. High-frequency electrical pulses, a drug that activates NMDA receptors, injection of a drug that activates calcium ions, and infusion of glutamate into the hippocampus are all methods that can induce LTP.

The Induction of Long-Term Potentiation in the Hippocampus Would Be